THE STATE OF ANTIBIOTIC USE AT SHYMKENT CITY CLINICAL HOSPITAL 1
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Anahtar Kelimeler:
antibacterial therapy; cross-sectional point-prevalence study; effectiveness of cephalosporins; cefazolin; ceftriaxone.Özet
In medical practice, monitoring the effectiveness of antibiotics and the susceptibility of pathogens plays an important role. According to the recommendations of the World Health Organization, controlling the efficacy and safety of antibacterial therapy can reduce infection resistance. Studying the patterns of antibiotic use in a hospital that provides emergency and planned specialized medical care is of both scientific and practical interest.
Aim of the study: To examine cases of antibacterial therapy prescriptions in the clinic and to assess the state of antibacterial therapy based on the results of a cross-sectional (point-prevalence) study.
Materials and methods: The study of antibacterial prescriptions was conducted in the clinical departments of City Clinical Hospital No. 1 in Shymkent. All medical records of patients receiving treatment at the time of the study were analyzed. A cross-sectional epidemiological method was used to assess the effectiveness of antibacterial therapy.
Results and conclusions: The prevalence of antibacterial therapy in the hospital in our study was 91.9%. Most patients (75%) received one antibiotic during treatment. The proportion of patients who were prescribed two antibacterial drugs was 17.6% of all patients receiving antibacterial therapy, while the combined proportion of those prescribed three or more antibiotics was 7.4%. Cephalosporins were used as initial antibacterial therapy in 81% of cases, and in 72.0% of these cases the effectiveness of the drugs was sufficient. Cefazolin and Ceftriaxone, which were used as the main antibiotics in postoperative patients, demonstrated effectiveness rates of 81% and 66.4%, respectively. The low effectiveness of ceftriaxone observed in our study highlights the need for enhanced monitoring of this antibiotic.