Biohybrid Systems for Waste Valorization: Synergizing Synthetic Biology and Green Engineering to Enable Circular Resource Recovery
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DOI:
https://doi.org/10.5281/zenodo.15744746Ключевые слова:
synthetic biology, waste valorization, biohybrid systems, circular economy, green engineeringАннотация
The increasing global momentum toward sustainable development has highlighted the imperative to convert waste flows into new value streams. This review discusses the novel paradigm of biohybrid systems that synergize synthetic biology, bioprocess engineering, and green chemistry to facilitate circular resource recovery from agricultural, industrial, and municipal wastes. Synthetic biology makes it possible to design genetically engineered microbes for enhanced bioconversion of recalcitrant waste substrates, and green engineering design makes it possible to design scalable, energy-conserving bioreactors and catalytic systems. Here, a critical analysis of system architectures like microbial consortia, biosensors, and metabolic pathway reengineering and their integrated functions towards valorizing carbon-rich residues to biofuels, organic acids, and bioplastics is covered. Case studies highlight successful lab-to-pilot scales, with a demonstration of their technical feasibility and their environmental benefits. However, there are challenges involving standardization, process optimization, and regulatory frameworks. This review invites interdisciplinarity to transcend the current challenges and facilitate the installation of robust, modular waste-to-resource technology. Integration of these technologies can revolutionize closing the loop on world waste and minimizing environmental contamination.
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